Iron Regulatory Protein 2

A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.

Also Known As:

IRE-BP2; IREB2 Protein; IRP-2 RNA-binding protein; IRP2 Protein; Iron-Responsive-Element Binding Protein 2; IRP 2 RNA binding protein; RNA-binding protein, IRP-2

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Lyases: 637
    - Carbon-Oxygen Lyases
      - Hydro-Lyases: 266
        Aconitate Hydratase: 286
        Iron Regulatory Protein 2: 46
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - RNA-Binding Proteins: 3262
      - Iron Regulatory Protein 2: 46
    - Iron-Binding Proteins: 172
      - Nonheme Iron Proteins
        Iron-Sulfur Proteins: 42
        Iron Regulatory Protein 2: 46
  - Nucleoproteins: 1870
    - RNA-Binding Proteins: 3262
      - Iron Regulatory Protein 2: 46
  - Metalloproteins: 164
    - Iron-Binding Proteins: 172
      - Nonheme Iron Proteins
        Iron-Sulfur Proteins: 42
        Iron Regulatory Protein 2: 46
  - Iron-Regulatory Proteins: 149
    - Iron Regulatory Protein 2: 46

Hayden Olivierre-Wilson Selected Research

Hayden Olivierre-Wilson Research Topics

Disease

Drug/Important Bio-Agent (IBA)